To evaluate brain activity and eye movements in children and adolescents with ADHD to assess the effect of treatment
- Conditions
- Health Condition 1: F902- Attention-deficit hyperactivity disorder, combined type
- Registration Number
- CTRI/2023/09/057306
- Lead Sponsor
- All India Institute of Medical Sciences New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria for Cases:
1.Children and adolescents diagnosed with ADHD as per DSM-5.
2.Age: 6-16 years.
3.Gender: Male.
4.Ability to comprehend instructions for testing.
5.Availability of at least 1 parent.
6.Assent from child and informed consent from parent.
7.Treatment naïve children.
8.Subjects that are advised Methylphenidate by the treating clinician.
Inclusion Criteria for Controls:
1.Healthy children.
2.Age: 6-16 years.
3.Gender: Male.
4.Ability to comprehend instructions for testing.
5.Availability of at least 1 parent.
6.Assent from child and informed consent from parent.
Exclusion Criteria for Cases:
1.History of any major medical illness.
2.History of any other psychiatric disorder (by clinical evaluation).
3.History of an episode of seizure.
Exclusion Criteria for Controls:
1.History of any major medical illness.
2.History of any psychiatric disorder (by clinical evaluation).
3.History of an episode of seizure.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To compare prefrontal cortical activity and saccadic eye movements in children with ADHD to healthy controls. <br/ ><br>2. To evaluate the acute effect of Methylphenidate on prefrontal cortical activity during saccadic eye movements in children with ADHD. <br/ ><br>Timepoint: Initial baseline assessment will be done after comprehensive clinical evaluation. Post intervention assessment will be done 2 hours after the intervention on the same day of baseline assessment.
- Secondary Outcome Measures
Name Time Method To compare prefrontal cortical activity with the severity of ADHDTimepoint: Initial baseline assessment will be done after comprehensive clinical evaluation. Post intervention assessment will be done 2 hours after the intervention on the same day of baseline assessment.