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Brain excitability in children with benign focal epilepsies

Not Applicable
Recruiting
Conditions
Benign Focal Epilepsy of Childhood
Neurological - Epilepsy
Registration Number
ACTRN12616000633482
Lead Sponsor
Clinical Professor Soumya Ghosh
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
80
Inclusion Criteria

Children with BFEC diagnosed by their treating paediatrician or neurologist.
Children with BFEC trait diagnosed by their treating paediatrician or neurologist.
Siblings and parents of children with BFEC or BFEC trait.

Exclusion Criteria

Children with intellectual disability
Children unable to cooperate
Presence of magnetically or electrically sensitive implants such as cardiac pacemakers, stimulators, pumps, cochlear implants, etc.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Cortical excitability will be compared between children with BFEC, their unaffected siblings and parents. Cortical excitability will be assessed using transcranial magnetic stimulation, [All participants will have TMS studies undertaken at enrolment. Children with BFEC or the EEG trait will have additional TMS studies undertaken at 6 months and 12 months after enrolment.]
Secondary Outcome Measures
NameTimeMethod
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