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Thoracic Paravertebral Blocks Using a Combination of Ropivacaine and Dexmedetomidine

Phase 4
Withdrawn
Conditions
Thoracic Paravertebral Blocks
Interventions
Registration Number
NCT03677115
Lead Sponsor
China Medical University, China
Brief Summary

The investigators designed a study to assess whether thoracic paravertebral blocks using a combination of ropivacaine and dexmedetomidine prolong nerve block duration.

Detailed Description

The investigators designed a study to assess whether thoracic paravertebral blocks using a combination of ropivacaine and dexmedetomidine prolong nerve block duration. The effects of dexmedetomidine have only been compared at lower doses. This trial examined the effect of greater dose of dexmedetomidine on thoracic paravertebral block analgesia duration.

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Patients were included in the study if they were ethnic Chinese,
  • American Society of Anesthesiologists (ASA) physical status I or II,
  • candidates for general anesthesia undergoing thoracic surgery
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Exclusion Criteria
  • Patients were excluded if they do not want to cooperate with the test,
  • had a history of radial artery puncture or coronary artery bypass grafting,
  • had acute vessel trauma,or had been diagnosed with Raynaud' disease,
  • had suffered from mental or neurological disorders
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Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
dexmedetomidine groupDexmedetomidinea combination of ropivacaine and dexmedetomidine
Primary Outcome Measures
NameTimeMethod
Change of analgesia durationChange from Baseline to 3 days after surgery

Change of thoracic paravertebral block analgesia duration

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

the First Hospital of China Medical University

🇨🇳

Shenyang, Liaoning, China

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