Thoracic Paravertebral Blocks Using a Combination of Ropivacaine and Dexmedetomidine
Overview
- Phase
- Phase 4
- Intervention
- Dexmedetomidine
- Conditions
- Thoracic Paravertebral Blocks
- Sponsor
- China Medical University, China
- Locations
- 1
- Primary Endpoint
- Change of analgesia duration
- Status
- Withdrawn
- Last Updated
- 4 years ago
Overview
Brief Summary
The investigators designed a study to assess whether thoracic paravertebral blocks using a combination of ropivacaine and dexmedetomidine prolong nerve block duration.
Detailed Description
The investigators designed a study to assess whether thoracic paravertebral blocks using a combination of ropivacaine and dexmedetomidine prolong nerve block duration. The effects of dexmedetomidine have only been compared at lower doses. This trial examined the effect of greater dose of dexmedetomidine on thoracic paravertebral block analgesia duration.
Investigators
Wen-fei Tan
Professor
China Medical University, China
Eligibility Criteria
Inclusion Criteria
- •Patients were included in the study if they were ethnic Chinese,
- •American Society of Anesthesiologists (ASA) physical status I or II,
- •candidates for general anesthesia undergoing thoracic surgery
Exclusion Criteria
- •Patients were excluded if they do not want to cooperate with the test,
- •had a history of radial artery puncture or coronary artery bypass grafting,
- •had acute vessel trauma,or had been diagnosed with Raynaud' disease,
- •had suffered from mental or neurological disorders
Arms & Interventions
dexmedetomidine group
a combination of ropivacaine and dexmedetomidine
Intervention: Dexmedetomidine
Outcomes
Primary Outcomes
Change of analgesia duration
Time Frame: Change from Baseline to 3 days after surgery
Change of thoracic paravertebral block analgesia duration