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Clinical Trials/NCT05890495
NCT05890495
Not yet recruiting
Phase 4

Patient-Applied Pretreatment Analgesia for Intrauterine Device Placement

Uniformed Services University of the Health Sciences1 site in 1 country120 target enrollmentJune 2023

Overview

Phase
Phase 4
Intervention
Lidocaine topical
Conditions
Contraception
Sponsor
Uniformed Services University of the Health Sciences
Enrollment
120
Locations
1
Primary Endpoint
Patient-reported pain level
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

The goal of this clinical trial is to perform a pilot study looking at the benefit of topical anesthetic application to the cervix by tampon prior to intra-uterine device insertion. The main question it aims to answer are:

  • Does patient tampon-applied local anesthetic prior to insertion of an intrauterine device (IUD) reduce procedural duration?
  • Does patient tampon-applied local anesthetic prior to insertion of an intrauterine device (IUD) reduce pain and improve patient perceptions of the procedure? Participants will place a tampon after dipping the tampon into the study-supplied medication (aqueous lidocaine or saline). Researchers will compare treatment and control groups to see if there is any difference in procedure time, difficulty or patient perceptions.

Detailed Description

This Pilot Randomized Double Blind Clinical Trial study will assess the effectiveness of patient-applied aqueous lidocaine via tampon as a pre-treatment prior to intra-uterine device placement. Subjects will apply the lidocaine or a saline placebo to the end of a standard tampon with a plastic applicator and then place the tampon 1 hour prior to the procedure. The tampon will be removed as the subject prepares for the procedure. The procedure team will measure the procedure time as well as the subject and provider impressions of the procedure. This data will be evaluated to compare the lidocaine to the control group.

Registry
clinicaltrials.gov
Start Date
June 2023
End Date
January 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mike Arnold

Associate Professor

Uniformed Services University of the Health Sciences

Eligibility Criteria

Inclusion Criteria

  • Request IUD insertion
  • Age 18 or older
  • Willingness to return for procedure after completing virtual study consent

Exclusion Criteria

  • Known allergy to viscous lidocaine or tampons
  • Current vaginal or cervical injury

Arms & Interventions

Aqueous lidocaine

Subject issued 5 ml jar of aqueous 4% lidocaine and will dip tampon distal end into jar for 30 seconds prior to placement.

Intervention: Lidocaine topical

Aqueous lidocaine

Subject issued 5 ml jar of aqueous 4% lidocaine and will dip tampon distal end into jar for 30 seconds prior to placement.

Intervention: Tampon

Saline

Subject issued 5 ml jar of sterile saline and will dip tampon distal end into jar for 30 seconds prior to placement.

Intervention: Tampon

Outcomes

Primary Outcomes

Patient-reported pain level

Time Frame: Obtained immediately after the procedure prior to the patient leaving the clinic

0-10 Visual analog scale

Procedure time

Time Frame: Measured during procedure

Time from uterine sounding to cutting strings (to allow for procedures where an IUD is removed prior to placing a new IUD)

Secondary Outcomes

  • Patient-reported satisfaction with procedure(Obtained immediately after the procedure prior to the patient leaving the clinic)
  • Provider-reported procedural difficulty(Obtained immediately after the procedure prior to the patient leaving the clinic)
  • Patient-reported interest in subsequent procedure(Obtained immediately after the procedure prior to the patient leaving the clinic)

Study Sites (1)

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