idocaine with ketamine in posterior spine fusio

Not Applicable

• Conditions: Anaesthesia

• Registration Number: PACTR202103785412583
• Lead Sponsor: Mostafa Mansour Hussein

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-03-15
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

60 adult patients aged between 18 - 65 years old, undergoing elective two or more levels of lumbar posterior spine fusion under general anesthesia will be enrolled in this study. Inclusion criteria include patients of both genders with American Society of Anesthesiologists (ASA) physical status I/II.

Exclusion Criteria

Known hypersensitivity to lidocaine or ketamine, pregnancy, severe renal disorder, hepatic dysfunction, cardiac arrhythmias, severe cardiac or pulmonary disease, increased intraocular pressure, history of psychiatric disorders, epilepsy, history of alcohol or drug abuse, patients receiving beta-blockers or antiarrhythmics, uncontrolled diabetes or hypertension, and patients unable to operate patient-controlled analgesia (PCA) pump.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The total intraoperative and postoperative opioid consumption and numeric pain scale.

Secondary Outcome Measures

Name	Time	Method
Sedation score, i.v. rescue analgesic, PONV and pruritis.