A 6-month Follow-up Study of Patients With Severe Fever With Thrombocytopenia Syndrome
- Conditions
- Severe Fever With Thrombocytopenia Syndrome
- Registration Number
- NCT06011902
- Lead Sponsor
- Tongji Hospital
- Brief Summary
This is a multi-center, retrospective clinical study to analyze the clinical features, laboratory indicators, imaging changes, treatment options and long-term prognosis in patients with sever fever with thrombocytopenia syndrome. All hospitalized patients with sever fever with thrombocytopenia diagnosed between 2016 and 2022 were included from the electronic medical record system of 8 centers, and demographics, hospitalization information, clinical information, laboratory or imaging examinations, treatment options, and outcomes were collected.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 1500
- Age and gender are not limited;
- Hospitalized patients diagnosed with severe fever with thrombocytopenia syndrome have at least one of the following laboratory test results: serum severe fever with thrombocytopenia syndrome bunyavirus (SFTSV)-specific IgM antibody positive or IgG antibody level increased more than 4 times; or positive for SFTSV RNA; or positive for SFTSV nucleic acid detected by real-time fluorescent quantitative RT-PCR; or SFTSV isolated from case specimens.
- Patients who were found to be positive for other tick-borne pathogens by PCR analysis of blood samples in the acute phase;
- It is difficult to conduct outpatient follow-up due to mental disorders, dementia, combined diseases such as osteoarthropathy, stroke, pulmonary embolism, etc. that lead to inability to move freely;
- No outpatient follow-up visit after discharge, and repeated confirmation by phone call still unable to get in touch;
- Due to living in other places, nursing homes, welfare homes, unable to participate in outpatient follow-up after making an appointment by phone;
- Currently participating in clinical trials of other drugs or medical devices;
- The researchers think it is not suitable for inclusion.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The presense of clinical symptoms of patients at 3 months and 6 months after discharge 3 months,6 months The number and severity of clinical symptoms of patients.
- Secondary Outcome Measures
Name Time Method Number of participants with different outcome of disease 6 months Number of participants who experience these events:
1. discharge with improvement
2. death
3. automatic discharge
Trial Locations
- Locations (8)
NO.1 Peoples Hospital of Guangshui
🇨🇳Guangshui, Hubei, China
People's Hospital Of Luotian County
🇨🇳Huanggang, Hubei, China
Huanggang Central Hospital
🇨🇳Huanggang, Hubei, China
People's Hospital of Macheng city Affiliated Hospital of Hubei Univerciy of science and technology
🇨🇳Macheng, Hubei, China
Suizhou Central Hospital
🇨🇳Suizhou, Hubei, China
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
🇨🇳Wuhan, Hubei, China
Yichang Third Peoples Hospital
🇨🇳Yichang, Hubei, China
Xianning Central Hospital
🇨🇳Xianning, Hubei, China