To look for a technique of anesthesia which is better for a children to decrease post operative complications caused due to inflammation mounted by used of heart lung machine
Not Applicable
Completed
- Conditions
- Health Condition 1: Q211- Atrial septal defectHealth Condition 2: Q213- Tetralogy of FallotHealth Condition 3: Q210- Ventricular septal defect
- Registration Number
- CTRI/2019/03/017985
- Lead Sponsor
- PGI THESIS GRANT
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
Pediatric patients undergoing cardiac surgery for atrial septal defect, ventricular septal defect and tetralogy of fallot under cardiopulmonary bypass
Exclusion Criteria
Patients with multiple organ abnormalities in addition to cardiac defect, congenital syndromes, know genetic disorders, congenital infections associated with developmental delay, pre existing immunological disease, on steroids, on immunomodulatory drugs, malignancies and where consent is refused
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the inflammatory response in pediatric patients undergoing cardiac surgery for atrial septal defect, ventricular septal defect and tetralogy of fallot under cardiopulmonary bypass using total intravenous anaesthesia and total inhalationalal Anaesthesia.Timepoint: Before surgery, 24 hrs and 48 hrs post surgery
- Secondary Outcome Measures
Name Time Method Cognitive functions in children above 4Timepoint: Before surgery, 24 hrs and 48 hrs post surgery;Echocardiographic parametersTimepoint: Before surgery, 24 hrs and 48 hrs post surgery;Fluid balanceTimepoint: Before surgery, 24 hrs and 48 hrs post surgery;Oxygenation statusTimepoint: Before surgery, 24 hrs and 48 hrs post surgery;Renal function by RIFLE criteriaTimepoint: Before surgery, 24 hrs and 48 hrs post surgery;Vasoactive inotropic scoreTimepoint: Before surgery, 24 hrs and 48 hrs post surgery;Ventilation hoursTimepoint: Post operative ventilation hrs requirement