Comparison the Effect of Dexmedetomidine with Levobupivacaine and Lebvobupivacaine in Scalp Nerves Block before Craniotomy on the Duration of Analgesia in Supratentorial Craniotomy

Phase 1

Completed

• Conditions: Elective supratentorial craniotomy; Scalp block, Dexmedetomidine, postcraniotomy analgesia, supratentorail tumor, levobupivacaine

• Registration Number: TCTR20200317002
• Lead Sponsor: Ramathibodi hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2020-01-31
• Study Start: 2020-03-17
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. Age 18-65
2. ASA 1-3
3. Elective first time supratentorial craniotomy
4. Informed consent before surgery

Exclusion Criteria

1. Patient refuse to participate
2. Chronic pain
3. Allergy to local anesthetic drug and Dexmedetomidine
4. Allergy to tramadol
5. Patient taking B-blocker
6. SBP<90 mmHg and HR <50 bpm before surgery
7. Coagulopathy
8. Scalp infection

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The time to the first analgesic requirement postoperatively Postoperative 24 hour The time to the first analgesic requirement

Secondary Outcome Measures

Name	Time	Method
Fentanyl consumption intraoperatively Intraoperative Fentanyl consumption,VAS at 1,4,8,12,24 hour postoperatively Postoperative 24 hour VAS scale,Tramadol requirement during the first 24 h postoperatively Postoperative 24 hour Tramadol requirement,Complication Postoperative 24 hour Hypotension, bradycardia, nerves injury, Nausea and vomiting, itching and sedation