Comparison the effects of Dexmedetomidine and Labetalol on blood pressure in maxillofacial fractures surgery

Phase 3

Conditions: Fracture of mandible.
Fracture of mandible
S02.6

Registration Number: IRCT20170408033291N3

Lead Sponsor: Qazvin University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 60

Inclusion Criteria

Ages 18 to 60 years
Class 1 & 2 of American Anesthesiologists (ASA) Association Classification
Fracture of mandible or maxilla

Exclusion Criteria

Class 3 or more of American Anesthesiologists (ASA) Association Classification
Heart Block
Heart Failure
Unstable Hemodynamic
Depression
Renal Failure
Raynaud's phenomenon
Sensitivity to lidocaine or beta-blockers
Deformity of Trachea
Lack of consent to participate in the study

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Systolic blood pressure. Timepoint: Before surgery, after intubation, after induction of hypotension, after bolus dose, 3, 5, 10, 15, 30, 60 min after bolus dose, end of operation and recovery. Method of measurement: Using a blood pressure monitor device.;Diastolic blood pressure. Timepoint: Before surgery, after intubation, after induction of hypotension, after bolus dose, 3, 5, 10, 15, 30, 60 min after bolus dose, end of operation and recovery. Method of measurement: Using a blood pressure monitor device.;Mean arterial blood pressure. Timepoint: Before surgery, after intubation, after induction of hypotension, after bolus dose, 3, 5, 10, 15, 30, 60 min after bolus dose, end of operation and recovery. Method of measurement: Using a blood pressure monitor device.

Secondary Outcome Measures

Name	Time	Method
Heart Rate. Timepoint: Before surgery, after intubation, after induction of hypotension, after bolus dose, 3, 5, 10, 15, 30, 60 min after bolus dose, end of operation and recovery. Method of measurement: Using cardiac monitoring device.