Comparing effect of Dexmedetomidine and Labetalol on Intraoperative blood loss in Rhinoplasty

Phase 3

Recruiting

Conditions: Condition 1: Systolic blood pressure. Condition 2: Diastolic blood pressure. Condition 3: Heart rate per minute. Condition 4: Mean arterial pressure. Condition 5: Bleeding rate.
Elevated blood-pressure reading, without diagnosis of hypertension
Other abnormalities of heart beat
Accidental puncture and laceration during a procedure, not elsewhere classified
R03.0
R00.8
T81.2

Registration Number: IRCT20150317021497N7

Lead Sponsor: Rafsanjan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 30

Inclusion Criteria

All subjects undergoing rhinoplasty surgery since the beginning of the study for 6 months
17-40 years

Exclusion Criteria

Drug sensitivity to Dexmedetomidine and labetalol
People with systolic blood pressure of 90 mmHg and lower
People with a heart rate of less than 60 beats per minute upon entering the operating room

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Systolic blood pressure. Timepoint: Before the start of surgery, after intubation, 20 minutes after intubation, during osteotomy, at the end of surgery, in recovery,. Method of measurement: Mercury sphygmomanometer.;Diastolic blood pressure. Timepoint: Before the start of surgery, after intubation, 20 minutes after intubation, during osteotomy, at the end of surgery, in recovery. Method of measurement: Mercury sphygmomanometer.;Heart rate. Timepoint: Before the start of surgery, after intubation, 20 minutes after intubation, during osteotomy, at the end of surgery, in recovery. Method of measurement: Pulse oximeter.;Bleeding rate. Timepoint: During osteotomy, at the end of surgery. Method of measurement: The difference in the weight of the consumed substances will be used to check the amount of bleeding. (weight of sterile gases after use + weight of suctioned liquids during surgery) - (weight of dry gases before use + amount of normal saline serum for washing the surgical site).

Secondary Outcome Measures