The comparison of Ondansetron and Metoclopramide effect on postoperative nausea and vomiting

Phase 3

• Conditions: Condition 1: Appendicitis. Condition 2: Cholecystitis. Condition 3: Nausea and vomiting.; Acute appendicitis; Cholecystitis; Nausea and vomiting

• Registration Number: IRCT201601232954N8
• Lead Sponsor: Azad Islamic University, Shahroud Branch

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

patients with appendicitis and cholecystitis that needs to surgery; ASA I or II; age between 15 to 70 years old; Patients satisfaction on participation in the study.
Exclusion criteria: Systolic blood pressure lower than 90 mmHg; Unstable hemodynamic; Opium addiction; history of uncontrolled diseases (Parkinson, Restlessness syndrome, Epilepsy, GI bleeding, Pheochromocytoma); Recent use of CNS depressant drugs; Recent use of antiemetic drugs; allergy to the drugs used in this study

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ausea severity. Timepoint: 1, 6,12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.;Number of vomiting. Timepoint: 1, 6,12 and 24 hours after surgery. Method of measurement: Questionnaire.

Secondary Outcome Measures

Name	Time	Method
Pain severity. Timepoint: 1 hour after surgery to 24 hours. Method of measurement: Visual Analogue Scale.;Need to excessive drugs. Timepoint: 1 hour after surgery to 24 hours. Method of measurement: Observation.