NL-OMON42708已完成不适用
Applicability of cornea confocal microscopy in the diagnosis of small fiber neuropathy. - Cornea confocal microscopy in small fiber neuropathy.
Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 225 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 225
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Healthy subjects (n<=20)
- •a. Male and female subjects of 18 years or older
- •b. One or less positive answers on the SFN-SIQ
- •c. Written informed consent;Patients (n<=200):
- •Those who are referred to our center for the analysis of possible small fiber neuropathy are eligible for participation in this study.
排除标准
- •Healthy subjects (n=20)
- •- Sensory symptoms in hands or feet or known with mono-/polyneuropathy.
- •- Known illnesses that can cause neuropathy, like diabetes mellitus, renal failure, alcohol abuse, rheumatoid arthritis, SLE, sarcoidosis, and thyroid dysfunction.
- •- History of diseases of the eye such as dry eyes, atopic keratoconjunctivitis, epithelial membrane basement dystrophies, cystic corneal disorders, which all affect corneal innervation.
- •- Patients with chronic glycemic exposure since this is a strong risk factor for corneal subbasal nerve loss.
- •- Use of medication (also in the past) known to possibly cause polyneuropathy.;Patients (n=200)
- •- History of diseases of the eye (such as mentioned above);Participants are excluded from this study when they do not want to be informed about defects or accidental findings which could be found during the pre-screening of the ophthalmologist.
研究者
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