Study for the effect of traditional Chinese medicine on the enhancement and attenuation of local advanced non-small cell lung cancer during radiotherapy and chemotherapy

Phase 1

• Conditions: on-small cell lung cancer

• Registration Number: ITMCTR2000003189
• Lead Sponsor: Shanghai Pulmonary Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Patients with locally advanced non-small cell lung cancer confirmed by pathology, who are not suitable for surgery and can accept radiotherapy and chemotherapy;
2. Patients aged 18-70 years old with ECoG PS 0-1 and expected survival time >=6 months;
3. For patients without major organ dysfunction and with basically normal heart, liver and kidney functions, the test indexes meet the following requirements: blood: leukocyte >4.0x10^9/L, neutrophil absolute value > 1.5x10^9/L, platelet count >100x10^9/L, hemoglobin >110g/L; liver function: serum bilirubin is 1.5 times lower than the maximum normal value; ALT and AST are 1.5 times lower than the maximum normal value; bun. Cr is within the normal range;
4. Pulmonary function: FEV1 >45%, DLCO >60% before treatment;
5. Patients without other cancers except stage I cervical cancer and skin basal cell carcinoma;
6. Patients with good compliance who can understand the situation of this study and sign the informed consent.

Exclusion Criteria

1. Patients with any acute or chronic diseases that are not suitable for radiotherapy and chemotherapy;
2. Patients with previous cancer history other than stage I cervical cancer and skin basal cell carcinoma, or who have undergone lobectomy or pneumonectomy;
3. Patients with active systemic infection or pulmonary or pericardial infection;
4. Pregnant or lactating women;
5. Patients with poor compliance with the protocol are not suitable for the study.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
adverse effects;