Binging on processed foods
- Conditions
- Binge Eating Disorder
- Registration Number
- NL-OMON29485
- Lead Sponsor
- n.a.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 30
Control subjects:
•Aged >18
•Female
•BMI >18,5 and <25
BED patients:
•Aged >18
•Female
•A primary diagnosis of BED according to DSM-IV criteria or subthreshold BED (an average of one binge eating episode a week)
•BMI >30
•Age <18
•BMI not >18,5 and <25 for control subjects and BMI <30 for BED patients
•Male sex
•Diabetes
•Any know food allergy or intolerance
•Renal or hepatic disease
•Use of medication known to affect glucose (for example prednisone) or lipid metabolism
•A current history of self-induced vomiting, misuse of laxatives, diuretics, enemas, diet pills or other weight controlling medications, fasting, or excessive exercise within the last 24 weeks;
•A comorbid diagnosis of psychotic disorder, self-damaging behaviors or mental deficiency
•Pregnancy
•Any contra-indication to MRI scanning
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Changes in brain connectivity and activity (BOLD signal), Z-scores for functional connectivity, eigen vector values) after ingestion of different food stimuli within groups <br>2.Differences in brain connectivity and activity (BOLD signa)l, Z-scores for functional connectivity, eigen vector values) after ingestion of different food stimuli between groups<br>
- Secondary Outcome Measures
Name Time Method 1.Visual Analogue Scale (VAS) scores for the level of hunger, thirst and satiety before and after ingestion of the food stimuli.