Determination of the bioavailability of folates
Not Applicable
- Conditions
- healthy volunteers
- Registration Number
- DRKS00010137
- Lead Sponsor
- ehrstuhl für Analytische Lebensmittelchemie (ALMC)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 2
Inclusion Criteria
healthy volunteers, 18 up to 30 years of age, BMI<30 kg/m2, non-smoker, written informed consent
Exclusion Criteria
-BMI>30 kg/m2
-smoker
-diseases affecting digetsion, resorption, and metabolism
-type TT of the methylentetrahydrofolate reductase (MTHFR) gene
-chronic diseases
-acute infektion
-pregnant and lactating women
-known allergies or intolerances against tested food
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measurement of folate vitamers in plasma after ingestion of strawberries or folate supplement or control using HPLC-DAD and LC/MS-MS. Blood samples are taken 2 hours before the testmeal. 0min, 15min,30min, 45min, 60min, 75min, 90min, 105min, 120min, 3h, 4h, 5h, 6h, 7h, 8h, 9h, and 10h after the testmeal.
- Secondary Outcome Measures
Name Time Method