Proton-pump inhibitor use and risk of gut-origin bloodstream infection: a hospital-based case-control study
Not Applicable
- Conditions
- gut-origin bloodstream infection
- Registration Number
- JPRN-UMIN000044753
- Lead Sponsor
- Ichinomiya-Nishi Hospital Department of gastroenterology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 309
Inclusion Criteria
Not provided
Exclusion Criteria
Patients under 20 years old were excluded. Patients who disagreed with enrollment of the study under the opt-out model were excluded. When patients had two or more episodes of bloodstream infections, only the first episode was included in the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Odds ratio of gut-origin bloodstream infection among PPI users and non-users as well as its 95% confidence interval adjusted for confounding factors
- Secondary Outcome Measures
Name Time Method In a sensitivity analysis that excluded individuals who did not have sufficient examination to find infectious focus, we calculated odds ratio of gut-origin bloodstream infection among PPI users and non-users as well as its 95% confidence interval adjusted for confounding factors.