Non-contrast 3D MR Angiography for Assessment of the Thoracic Aorta in Pregnancy

Completed

• Conditions: Magnetic Resonance Imaging; Pregnancy

• Registration Number: NCT02793570
• Lead Sponsor: University Hospital Birmingham NHS Foundation Trust

Brief Summary

Introduction: Native magnetic resonance angiography (MRA) is recommended to assess the thoracic aorta during pregnancy, avoiding the risks of ionising radiation and contrast agent administration. This guidance is however, based only on consensus opinion supported by limited case reports (level of evidence C).

Aim: To evaluate the feasibility of performing native 3D steady-state free-precession (SSFP) MRA in pregnant subjects with inherited aortopathy to guide timing and mode of delivery.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01
• Study First Submitted: 2016-06-03
• Study First Submitted QC: 2016-06-03
• Study First Posted: 2016-06-08
• Primary Completion: 2016-10
• Study Completion: 2016-10
• Status Verified: 2016-11
• Last Update Submitted: 2016-11-08
• Last Update Posted: 2016-11-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 15

Inclusion Criteria

• Any pregnant subject with a history of familial aortopathy

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Gestation at delivery	40 weeks
Completion of non-contrast 3D MRA aorta	40 weeks

Trial Locations

Locations (1)

QEHB; 🇬🇧 Birmingham, United Kingdom