CArdiac magnetic resonance perfusioN imaging for SELection of patients for additional invasive evaluation after CT coronary angiography (CANSEL)

Recruiting

• Conditions: coronary atherosclerosis; MRI; 10011082

• Registration Number: NL-OMON31103
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 75

Inclusion Criteria

1. Suspected obstructive CAD on CT-CA
2. Planned invasive coronary angiography

Exclusion Criteria

1. Previous myocardial infarction
2. Previous percutaneous coronary intervention or coronary artery bypass grafting
3. Contraindications for MRI
4. Possible pregnancy and/or breast feeding
5. Inability to breath hold for up to 15 seconds
6. Inability to give reliable informed consent
7. Known claustrophobia
8. Unstable coronary artery disease
9. Known allergy to contrast material
10. Renal insufficiency
11. COPD.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>We expect a high sensitivity and specificity for first pass magnetic resonance<br /><br>imaging to detect a significant coronary artery stenosis as determined by FFR.<br /><br>Determination optimal cut of value.<br /><br>There is no benefit for the individual patient. In the future in patients with<br /><br>coronary stenosis identified by CT-CA, myocardial perfusion MRI will predict<br /><br>who may benefit from coronary revascularisation. Furthermore the combination of<br /><br>CT-CA, and myocardial perfusion study using magnetic resonance will also<br /><br>predict who do not have a coronary stenosis and therefore do not need ICA.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>NA</p><br>