MPV and NLR as Predictors of SBP Diagnosis
Completed
- Conditions
- Spontaneous Bacterial Peritonitis
- Interventions
- Diagnostic Test: Measurement of mean platelet volume (MPV) and blood neutrophil to lymphocyte ratio (NLR)
- Registration Number
- NCT04775420
- Lead Sponsor
- Sohag University
- Brief Summary
The aim of the study is to investigate the clinical utility of mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) as diagnostic markers for spontaneous bacterial peritonitis (SBP).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 332
Inclusion Criteria
- Decompensated liver cirrhosis ascetic patients.
Exclusion Criteria
- Immunocompromised patients.
- Patients who had received antibiotics before hospital admission.
- Patients on anticoagulant medications, NSAIDs, or oral contraceptive drugs.
- Patients with heart failure, diabetes mellitus, hypertension, hyperlipidemia, peripheral vascular disease, hematological disorders, and neoplastic disorders and patients with clinically overt hypothyroidism or hyperthyroidism or with clinically and laboratory-evident autoimmune diseases.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Group 2 Measurement of mean platelet volume (MPV) and blood neutrophil to lymphocyte ratio (NLR) Ascetic patients with spontaneous bacterial peritonitis Group 1 Measurement of mean platelet volume (MPV) and blood neutrophil to lymphocyte ratio (NLR) Ascetic patients without spontaneous bacterial peritonitis
- Primary Outcome Measures
Name Time Method The utility of MPV as non-invasive predictor of SBP 1 year It will be measured from CBC
The utility of NLR as non-invasive predictor of SBP 1 year It will be measured from CBC
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Sohag Faculty of Medicine
🇪🇬Sohag, Egypt