Positron emission tomography (PET) measurement of the displaceability of [11C]FLB 457 from extra-striatal dopamine D2 receptors in ma
Completed
- Conditions
- ot Applicable: MetabolismNot Applicable
- Registration Number
- ISRCTN23418225
- Lead Sponsor
- Record Provided by the NHSTCT Register - 2004 Update - Department of Health (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 16
Inclusion Criteria
Volunteers: 16. Males 25-65 yrs, females 45-65 yrs.
Exclusion Criteria
Not provided at time of registration
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie [11C]FLB 457's binding affinity to extra-striatal dopamine D2 receptors in PET imaging?
How does [11C]FLB 457 PET imaging compare to other dopamine D2 receptor ligands in measuring receptor occupancy?
Which biomarkers correlate with [11C]FLB 457 displaceability in extra-striatal dopamine D2 receptor studies?
What are the safety profiles and radiation exposure risks of [11C]FLB 457 in interventional PET studies?
Are there combination approaches using [11C]FLB 457 PET with other neuroimaging techniques for dopamine system evaluation?