Sleep Inertia and Functional Connectivity

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Other: fMRI

• Registration Number: NCT03058159
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

The aim of the study is to investigate the functional connectivity between the brain regions of the default mode network before and after a 40 min nap slot in the afternoon. The hypothesis is that connectivity between brain regions will be decreased after the nap as compared to before the nap.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-03-05
• Study First Submitted: 2017-02-09
• Study First Submitted QC: 2017-02-15
• Study First Posted: 2017-02-20
• Primary Completion: 2017-05-24
• Study Completion: 2017-07-03
• Status Verified: 2018-06
• Last Update Submitted: 2018-06-08
• Last Update Posted: 2018-06-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 55

Inclusion Criteria

• 65 > age > 18
• high or law dream recall frequency

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Exclusion Criteria

• history of psychiatric or neurologic or sleep pathologies
• counter indication for MRI

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Subjects with a high dream recall frequency	fMRI	-
Subjects with a law dream recall frequency	fMRI	-

Primary Outcome Measures

Name	Time	Method
Measure: Change of correlation values between the BOLD (Blood Oxygenation Level Dependent) signal time series of the brain regions of the default mode network (DMN) between the scans before and after the nap slot.	fMRI scans will be acquired 5 min before, 5 min after and 25min after the nap slot.	The hypothesis is that connectivity between the brain regions of the default mode network will be decreased after the nap as compared to before the nap and that it will be more the case for subjects with a high dream recall frequency as compared to subjects with a law dream recall frequency. fMRI scans will be acquired before and after a 40 min nap slot in the afternoon. Functional connectivity between brain region will be assessed analyzing the scans with the functional connectivity toolbox (CONN) of the Statistical Parametric Mapping (SPM) software.

Trial Locations

Locations (1)

CH le VINATIER; 🇫🇷 Bron, France