Antibiotic Prophylaxis in Mesh Repair of Inguinal Hernias
Phase 4
Completed
- Conditions
- Inguinal Hernia
- Interventions
- Drug: sefazolin
- Registration Number
- NCT01264003
- Lead Sponsor
- Diskapi Teaching and Research Hospital
- Brief Summary
Inguinal hernia repairs is clean surgical procedures. However infection may be a concern when prosthetic materials are used. This prospective randomized study has been set to observe if antibiotic prohylaxis is of benefit in mesh repair of inguinal hernias.
- Detailed Description
There are two group in the study. Control group received no antibiotic prohylaxis, whereas a single dose 1 gr. intravenous cefazoline is given to the patient in prophylaxis arm of the study. 30-days surgical site infection rates and 1 year prosthetic intervention late infection rates are observed and recorded. Side effects of antibiotic used are also recorded.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
inguinal hernia repair -
Exclusion Criteria
uncontrolled diabetes mellitus,
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 sefazolin Antibiotic prohylaxis / Lichtenstein repair
- Primary Outcome Measures
Name Time Method Surgical site infection 30 days postoperatively
- Secondary Outcome Measures
Name Time Method Drug side effects 5 days postoperatively 1-year prosthetic repair surgical site late infection rate 1 year