Comparison between clinical effects of intra-articular ozone and intra-articular steroid injection in the treatment of chronic ankle osteoarthritis
- Conditions
- Chronic Osteoartritis of Ankle.Primary osteoarthritis, unspecified ankle and footM19.079
- Registration Number
- IRCT20100827004641N19
- Lead Sponsor
- Physical Medicine and Rehabilitation Research Center of Tabriz
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Existence of symptoms of ankle osteoarthritis for at least 3 months
Minimum score of 3 in the criterion (VAS)
Absence of inflammatory rheumatic diseases
Failure to respond to conservative drug and physiotherapy treatments during the past 6 months
Satisfaction of patients participating in the study
rug and physiotherapy treatments during the past 6 months
Aged 45 years and older
Severe osteoarthritis (Grade 4 candidates for joint replacement surgery)
Rumatic disease
Clearly visible deformity of the ankle
Ankylosis
Ozone contraindications include: -Hyperthyroidism -Thrombocytopenia -Pregnancy Recent history of heart attack G-6PD deficiency
Definitive and relative contraindications to steroid injections include: Bacteremia, sepsis, intra-articular or pre-uricular infection, history of post-injection allergies Specific skin lesion at the injection site
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount af Reduce in pain after injection. Timepoint: 1 month after injection and 6 months after injection. Method of measurement: FADI questionnaire.
- Secondary Outcome Measures
Name Time Method Improvement of function and reduce in pain of ankle. Timepoint: Before,1 month an 6 months after injection. Method of measurement: FADI questionnaire.