Evaluation of venous hypertension in craniosynostosis

Recruiting

• Conditions: Craniosynostosis; premature closure of one or more cranial sutures; 10021666

• Registration Number: NL-OMON42060
• Lead Sponsor: Plastische en Reconstructieve Chirurgie en Handchirurgie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

- Premature synostosis of the metopic or sagittal suture.
- Presentation at the outpatient clinic before the fontanel has closed.
- Patient will be treated with surgery.

Exclusion Criteria

- Closure of multiple sutures or syndrome diagnosis.
- Known with other brainmalformation

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters follow from the ultrasounds. With (transcranial)<br /><br>colour-coded duplex sonography the diastolic, systolic and mean blood flow<br /><br>velocities are measured. Pulsatility and resistive index (PI and RI) will be<br /><br>calculated. For the individual patient the endpoint of this study is reached<br /><br>after the second ultrasound.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>N/A</p><br>