A randomized controlled clinical study of Qinghua Zhixie Recipe in Treating Irritable Bowel Syndrome with Spleen Deficiency and Damp-Heat
- Conditions
- Irritable Bowel Syndrome
- Registration Number
- ITMCTR2000003959
- Lead Sponsor
- Changshu Hospital of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. According to IBS-D diagnostic criteria of Chinese and Western medicine,
2. gender is not limited, age is 18-70 years old;
3. patients and their families sign informed consent.
1. Diarrhea caused by Crohn's disease, ulcerative colitis, chemotherapy-induced diarrhea, virus and bacterial infection, diet, lactose intolerance and other causes;
2. Complicated with other digestive tract diseases, such as gastrointestinal tumor, anal disease, intestinal obstruction, perforation, tumor and anal disease;
3. Pregnant, lactation or other cardiovascular and cerebrovascular serious diseases;
4. Taking nonsteroidal drugs within 1 month Anti inflammatory drugs, aspirin or other drugs that may affect visceral sensitivity;
5. Participants in other clinical trials;
6. Patients with allergic history.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method total effective rate;Total score of TCM Syndromes;
- Secondary Outcome Measures
Name Time Method VIP;TLR4 signaling pathway related gene mRNA;TLR4 signaling pathway related gene mRNA;NPY;NPY;