A randomized controlled trial for Xiao-Qing-Long Decoction in the treatment of refractory asthma
- Conditions
- refractory asthma
- Registration Number
- ITMCTR1900002783
- Lead Sponsor
- Hospital of Chengdu University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Agde 18-65 years men or women, diagnosis of bronchial asthma for at least 1 year;
2. Patients conform to the diagnostic criteria of Western medicine refractory asthma;
3. Patients conform to the diagnostic standard of Chinese medicine asthma External Cold and Internal Fluid Syndrome;
4. Patients own good ability to read, understand and write research-related materials and comply with all trail requirements on a voluntary basis;
5. Patients voluntarily participate in research and sign informed consent form.
1. Patients have a respiratory infection within 4 weeks;
2. Patients with chronic lung diseases require intervention or treatment such as chronic obstructive pulmonary disease, interstitial lung disease, active tuberculosis, bronchial dilation ;
3. Patients with serious primary diseases such as severe mental and psychological disorders, heart and brain vessels diseases, liver and kidney diseases, endocrine diseases, hematopoietic system diseases and malignant tumors ;
4. Patients take antibiotics within 3 months and eat yogurt or probiotics within 1 month;
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5. Patients are unwilling or unable to change the current treatment plan;
6. Patients are known to be allergic to trail drugs or a certain Chinese medicine of this study;
7. Women are breastfeeding, pregnant or preparing for pregnancy;
8. Patients have more than 15 packs per year of smoking history ;
9. Patients have participated in other clinical studies in the past six months.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Asthma Control Test(ACT) score;
- Secondary Outcome Measures
Name Time Method Pulmonary function(FEV1, FEV1/FVC, daytime and night peak expiratory flow(PEF));Average daily use of drugs that relieve asthma;Curative effect of TCM syndrome;Asthma Quality of Life Questionnaire(AQLQ);Changes in the composition of intestinal flora in the faeces of subjects;