Comparison of the efficacy of oral, intravenous and topical Tranexamic acid in reducing bleeding after total knee arthroplasty
Phase 3
Recruiting
- Conditions
- Total knee arthroplasty.Unspecified complication of internal orthopaedic prosthetic device, implant and graft
- Registration Number
- IRCT20180411039272N1
- Lead Sponsor
- Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 135
Inclusion Criteria
Patients undergoing total knee arthroplasty admitted in Amiralmoemenin and Valiasr hospital in Arak
Patients between 30 and 80 years old
Patient with ASA class1 and 2
Patients who have informed consent for presence in mentioned project
Patients who are operated by one surgeon
duration of operation time between 90 and 180 minutes
Exclusion Criteria
All Patients out rang of 30 to 80 years old
Lack of Informed consent
Patients with multiple surgeries
Patients who are sensitive to Tranexamic acid
Patients undergoing general anesthesia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean of bleeding in patients undergoing arthroplasty after operation. Timepoint: 4 and 24 and 48 hours after operation. Method of measurement: Millileter.;Mean of bleeding during of operation. Timepoint: During of operation. Method of measurement: Millileter.;Number of come back again of patients to operation room. Timepoint: 48 hours after operation. Method of measurement: Number.;Mean of hemoglobin. Timepoint: 4 and 24 and 48 hours after operation. Method of measurement: Milligram in millileter.
- Secondary Outcome Measures
Name Time Method