A clinical study to understand whether treatment with oral fluid therapy is better than or as good as treatment with intravenous fluid therapy in treatment of dehydration at pH values greater than or equal to 7.25 during treatment of dehydration in diabetic ketoacidosis in children.

Not Applicable

• Conditions: Health Condition 1: null- patients having diabetic ketoacidosis in paediatric age group

• Registration Number: CTRI/2018/06/014472
• Lead Sponsor: Kola Shourya Vijay Tej

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

All Children of age less than 18 years fulfilling the case definition of diabetic ketoacidosis who present to pediatric emergency as per ISPAD guidlines -International society for pediatric and adolescent diabetes

Exclusion Criteria

Children who fail to achieve a pH>=7.25 or fail to achieve a GCS >12 or children with a falling GCS by two points from baseline.

Children admitted with DKA and who are partially treated in outside hospital.

Children with co-morbidities where fluid therapy cannot be altered.

Children with comorbidities which contraindicate oral feed.

Children whose parents are not willing to consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proprortion of children having successful hydration correction at the end of 48 hrs in both groups.Timepoint: from time of initiation of therapy to end of 48 hours of therapy

Secondary Outcome Measures

Name	Time	Method
Comparative analysis of time taken by intravenous fluid versus oral fluid therapy after resolution of acidosis pH â?¥ 7.25 in DKA to complete normalization of pH, bicarbonate, and ketonuriaTimepoint: from time of initiation of therapy to end of 48 hours of therapy