Comparing the effects of yogurt containing Akkermansia Muciniphilia with yogurt containing Lactobacillus Acidophilus on body composition, anthropometric and biochemical indices, appetite, and depression scores in overweight or obese adults

Phase 3

Recruiting

• Conditions: Overweight and obesity.; Overweight and obesity

• Registration Number: IRCT20230522058257N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 November 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

Aged 20 - 50 years and not being menopause for females
Being overweight or obese (Body mass index higher than 25)
Not allergic to milk protein and Not lactose intolerant,not being gluten-intolerant
Not suffering from known endocrine-related obesity, Inflammatory bowel disease, Irritable bowel syndrome, nouropathy, gastroparesis and gastrointestinal disorders at the beginning of the study
Not suffering from thyroid diseases, diabetes, kidney disease, rheumatic diseases and migraine headache at the baseline
did not use antibiotics for 2 months before the beginning of the study
didn't take probiotic, prebiotic, and omega 3 supplements for 1month before the study
Not taking part in other studies for 6 months before the study
No weight reduction over 6 Kg in the last 3 months prior to the study
no history of hospitalization or any surgery and bariateric surgery for 3 months before the study and 6 months after entering the study
Not following special diets such as vegetarian or gluten free or weight-reducing diets
Not infected with Covid-19 or any other infections or any hospitalization for 1 month before the study

Exclusion Criteria

planning for pregnancy for 6 months after the study and not having breast-feeding
heavy alcohol use

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Waist circumference. Timepoint: At the beginning of the study (before the intervention) and the end of the study (8 weeks after the intervention). Method of measurement: stadiometer.;Body weight. Timepoint: At the beginning of the study (before the intervention) and the end of the study (8 weeks after the intervention). Method of measurement: scale.;Body mass index. Timepoint: At the beginning of the study (before the intervention) and the end of the study (8 weeks after the intervention). Method of measurement: By calculating using the formula with using height and weight.