A study for the effects of ingestion of yogurt in adults with discomfort of eyes and nose :A randomized, double-blind, placebo controlled trial
- Conditions
- Healthy adults
- Registration Number
- JPRN-UMIN000027791
- Lead Sponsor
- TTC Co., Ltd.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Not provided
(1)Subjects who routinely take foods or medicines containing of lactic acid bacteria. (2)Subjects who routinely take foods or medicines affecting the test result (3)Subjects who have history of regular visits of otorhinolaryngology or planned to clinic visits (4)Subjects who has received a diagnosis of seasonal allergic rhinitis (pollen allergy) (5)Subjects with acute rhinitis, sinusitis or hypertrophic rhinitis (6)Subjects with bronchial asthma (7)Subjects who are under treatment or have a history of serious disease(e.g., diabetes, liver disease, kidney disease, or heart disease) (8)Subjects who are under medication(e.g., hyposensitization)which may influence the outcome of the study (9)Subjects with allergies to the test food in the study (10)Subjects judged as unsuitable for the study by the investigator for laboratory evidence or cardiopulmonary function (11)Subjects who have a disease requiring regular medication or a history of serious diseases for which medication was required (12)Subjects who are judged as unsuitable for the study based on the results of clinical and physical examination on preliminary examination (13)Subjects who have participated in other clinical study within the last one month prior to the current study or are planned to participate in other clinical study after informed consent for the current study (14)Subjects who are planned to become pregnant after informed consent for the current study or are pregnant or lactating (15)Subjects who are judges as unsuitable for the study based on the results of lifestyle questionnaire (16)Subjects who are judged as unsuitable for the study by the investigator for other reason
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Questionnaire of discomfort of eyes and nose,Diary. Evaluate at points of 12-week and 4-week, 8-week
- Secondary Outcome Measures
Name Time Method Specific IgE(RAST), IFN-Gamma, IL-13, Total IgE(RIST)