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The Impact of Branched-Chain Amino Acid Metabolism on Limb Dysfunction in PAD

Not Applicable
Completed
Conditions
Peripheral Arterial Disease
Registration Number
NCT03490968
Lead Sponsor
Vanderbilt University Medical Center
Brief Summary

Test the theory that abnormalities in the large blood vessels that deliver blood to your leg and the very small blood vessels in your leg's muscles (invisible to the eye) work together to worsen your leg function and walking.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
80
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
C3/C5acylcarnitine levels in healthy control subjects.baseline
C3/C5 acylcarnitine levels in PAD surgical bypass groupChange from baseline to 12 weeks
C3/C5acylcarnitine levels in PAD exercise group after 12 weeksChange from baseline to 12 weeks
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Vanderbilt University Medical Center

πŸ‡ΊπŸ‡Έ

Nashville, Tennessee, United States

Vanderbilt University Medical Center
πŸ‡ΊπŸ‡ΈNashville, Tennessee, United States

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