Progression of the dopaminergic deficit of akinetic-rigid and tremordominant Parkinson's Disease patients

• Conditions: G20; Parkinson disease

• Registration Number: DRKS00003110
• Lead Sponsor: niklinik KölnKlinik für Neurologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-06-20
• Study Completion: 2011-10-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

male or female patients with the clinical diagnosis of an idiopathic Parkinson syndrome
- previous FP-CIT-SPECT 2-5 years before
- patient in the age between 30 and 80 years
- patients have to given written informed consent

Exclusion Criteria

- patients with another disease which leads to cognitive impairment (tumor, vascular incidents, etc.)
- patients with depression or dementia

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
visual type in the dopamine transporter single photon emission computertomography (DaT-Scan)

Secondary Outcome Measures

Name	Time	Method
nited Parkinson's Disease Rating Scale (UPDRS) part III: assessment of parkinsonian symptoms <br>Beck-Depression-Inventory-2: assessment of depression<br>DemTect: assessment of dementia<br>Parkinson Neuropsychiatric Dementia assessment (PANDA): assessment of Parkinson's disease related dementia<br>Hypomania-questionnaire: assessment of hypomania<br>Barrett Impulsiveness Scale: assessment of impulsiveness<br>Nonmotor-symptoms Questionnaire<br>