Comparison of changes in ferritin and hs-CRP serum level in medical and surgical treatment of nasal polyps: randomized clinical trial
- Conditions
- Sinonasal polyposis (SNP) inflammatory disease of the nasal mucosa hs-CRPFerritinSinonasal polyposis (SNP)inflammatory disease of the nasal mucosahs-CRPFerritin
- Registration Number
- TCTR20170220001
- Lead Sponsor
- Shahid Sadoughi University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 66
Patient who have not treated sinonasal polyposis, aged between 20 to 60 years and lund-macky score upper than 11 was included in this study. The lund-mackay scoring system which is the most popular system to evaluate the Computed tomography in sinus disease was used to evaluate the patients for the procedures they needed. In this scoring system a score of 0-1 or 2 were given to patient with normal, partial opacification, and total opacification respectively for each of this subsites: 1) anterior ethmoid 2) posterior ethmoid 3) frontal 4) maxillary and 5) sphenoid sinus on each side and for patent or obstructed osteomatal cavity in each side would give a 0 or 2 respectively. In this scoring system the maximum score were 12 and 24 for both sides. We assumed patients in two classes based on lund-mackay scoring, first group; mild (0-11), second group; severe (12-24), and the patient who were in class 2 can be included in our study.
We excluded patients with acute and chronic inflammation such as malignancy and rheumatism disease, infectious conditions, history of sinonasal Endoscopic surgery, using anti inflammation drugs, patients with anemia and received iron or blood products 1 month before study and incident of above conditions during one month follow up of our patients.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method hs-CRP 24 hoour and 30 days after start ng/ml
- Secondary Outcome Measures
Name Time Method serum ferritin 24 hoour and 30 days after start mg/