Reversibility of cerebrovascular endothelial dysfunction in patients with diabetes

Completed

• Conditions: Diabetes; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN15728912
• Lead Sponsor: niversity of Glasgow (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-10-27
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

1. Type II diabetes <5 years duration
2. Age >40 years
3. Normal full Bruce protocol exercise tolerance test

Exclusion Criteria

1. >70% internal carotid artery (ICA) stenosis
2. Significant comorbidity
3. Contra-indication to administration of angiotensin II receptor blocker (ARB)/angiotensin converting enzyme (ACE)-1/beta-blocker
4. Ongoing treatment with ARB/ACE1/beta-blocker unless can be withdrawn 4 weeks prior to randomisation

Study & Design

• Study Type: Interventional
• Study Design: Not specified