ISRCTN77942127
Completed
未知
Reversibility of impaired cerebrovascular reactivity in patients with hypertension: comparison of losartan and atenolol
niversity of Glasgow (UK)0 sites13 target enrollmentOctober 27, 2005
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- niversity of Glasgow (UK)
- Enrollment
- 13
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Male: 50\-80 years
- •2\. Electrocardiogram (ECG) evidence of left ventricular hypertrophy (LVH)
- •3\. Blood pressure (BP) 150\-200/90\-115
Exclusion Criteria
- •1\. \>70% internal carotid artery (ICA) stenosis
- •2\. Middle cerebral artery (MCA) stenosis
- •3\. Contra\-indication to losartan, atenolol or acetazolamide
- •4\. Serum creatinine \>130 µmol/l
- •5\. Prior treatment with angiotensin converting enzyme (ACE)\-1/angiotensin II receptor blocker (ARB)/beta blocker unless able to stop 4 weeks prior to recruitment
Outcomes
Primary Outcomes
Not specified
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