Multiphoton Laser Scanning Microscopy in Cutaneous Optical Pathology

• Conditions: Optical Biopsy; Cutaneous Pathology; Dermatopathology

• Registration Number: NCT00508781
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

We use multiphoton laser scanning microscopy to observe cutaneous anatomy and pathology. The study aims to compare surgical specimen by conventional pathology slice with the image by non-invasive multiphoton laser scanning microscopy.

Detailed Description

For skin diseases, the most convincing method for diagnosis to date is surgical biopsy. However, a skin biopsy is an invasive procedure which carries the risk of tissue damage, wound infection and scar formation. To solve the inconvenience from surgical biopsy, multiphoton laser scanning microscopy is a developing, non-invasive method for observing the cutaneous anatomy and pathology. Multiphoton laser scanning microscopy is good in tissue penetration and resolution with less tissue damage. The study aims to compare surgical specimen by conventional pathology slice with the image by non-invasive multiphoton laser scanning microscopy. A good correlation in multiphoton image may serve as optical biopsy for cutaneous pathology and spare the invasive procedure of skin biopsy.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Status Verified: 2002-11
• Study Start: 2002-11
• Study First Submitted: 2007-07-26
• Study First Submitted QC: 2007-07-26
• Last Update Submitted: 2007-07-26
• Study First Posted: 2007-07-30
• Last Update Posted: 2007-07-30
• Study Completion: 2012-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• Patients receiving cosmetic surgeries such as removal of moles

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Exclusion Criteria

• No special exclusion criteria

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei, Taiwan