Use of Multiphoton Microscopy in the Diagnosis of Cancer
Phase 1
Completed
- Conditions
- Bladder CancerProstate Cancer
- Interventions
- Other: Multiphoton microscopy
- Registration Number
- NCT00652210
- Lead Sponsor
- Weill Medical College of Cornell University
- Brief Summary
Multiphoton microscopy (MPM) has been shown to be able to image tissue at a cellular level. Our project will initially evaluated the ability of MPM imaging to distinguish normal bladder urothelium from atypical and malignant urothelium in the ex vivo setting. After development of sufficient criteria, we plan to develop an endoscopic bladder probe that will provide a non-invasive means to image the interior of the bladder at the cellular level, which would provide direct evidence of the presence of tumor without a biopsy. After exhibiting usefulness of MPM imaging for bladder cancer, we will look at other organs beginning with the colon.
- Detailed Description
Same as above
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 344
Inclusion Criteria
- Anyone who presents with bladder and/or prostate cancer
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description MPM Multiphoton microscopy Subject tissue was reviewed using multiphoton microscopy
- Primary Outcome Measures
Name Time Method After several delays, the multiphoton microscope has been delivered to Weill Cornell Medical College. We have been using this time to set-up and fine tune the multiphoton microscope. As of current, no negative events have occurred. 10/14/2007 to 2/15/2008
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Weill Cornell Medical College
🇺🇸New York, New York, United States