Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy
- Conditions
- Skin Lesion
- Interventions
- Device: MPTflex-multiphoton microscopy-based tomograph.
- Registration Number
- NCT01771718
- Lead Sponsor
- University of California, Irvine
- Brief Summary
The purpose of this pilot study is to employ multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin lesions for characterization of their morphologic and functional features. .
- Detailed Description
This study is performed using a multiphoton microscopy-based tomograph (MPTflex) developed by JenLab, GmbH (Germany) to image non-invasively normal and lesional skin. Skin lesions are imaged by multiphoton microscopy and images are compared to those obtained from histopathology through standard of care processed skin biopsies.
Any biopsies will be performed by the health care provider as a standard of care procedure.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 250
- Male or Female all age groups
- Ability to understand and carry out subject instructions
- Pregnant women
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Human skin MPTflex-multiphoton microscopy-based tomograph. Multiphoton microscopy imaging to collect information about changes in skin cells and fibrilar structure.
- Primary Outcome Measures
Name Time Method high-resolution images of skin up to 12 months The complementary imaging modalities (MPM, MI) will provide insights into a better understanding of the relationship between microscopic and macroscopic properties of the skin.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Beckman Laser Institute Medical Clinic
🇺🇸Irvine, California, United States