Development and Relationship Between Resilience and Anxiety and Depression in Elderly Gastric Cancer Survivors

Completed

• Conditions: Anxiety; Depression; Resilience

• Registration Number: NCT06033716
• Lead Sponsor: Nanjing Medical University

Brief Summary

This study will explore the dynamic interaction between mental resilience, anxiety and depression in elderly patients with gastric cancer 1 year after surgery, in order to better understand the role of these two factors in patients' mental health, and provide accurate insights for clinical practice and targeted psychological support strategies.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-01
• Primary Completion: 2022-10-31
• Study Completion: 2022-10-31
• Study First Submitted: 2023-08-26
• Status Verified: 2023-09
• Study First Submitted QC: 2023-09-09
• Last Update Submitted: 2023-09-09
• Study First Posted: 2023-09-13
• Last Update Posted: 2023-09-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 412

Inclusion Criteria

• diagnosed with gastric cancer by endoscopy or pathology
• age ≥60 years old
• radical gastrectomy was proposed
• be able to communicate simply in writing and verbal

Exclusion Criteria

• received preoperative radiotherapy or chemotherapy;
• combined with other sites of malignant tumors;
• combined with severe heart, liver, lung and renal insufficiency;
• recent using hormones, immunosuppressants;
• with physical disabilities.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
resilience	immediately after surgery (T1), three month post-surgery (T2), six months post-surgery (T3), 12 months post-surgery (T4)	The Chinese version of 10-item Connor-Davidson Resilience Scale (CD-RISC-10), translated and revised by Chinese scholars, was used in this study. Cronbach's alpha for the Chinese version was 0.855, indicating good internal consistency. It was also applied to cancer patients in China. Each of which was scored on a 5-point Likert scale, ranging from 1 to 5 points, from "Never" to "Almost always", with higher scores representing a higher level of psychological resilience.
anxiety	immediately after surgery (T1), three month post-surgery (T2), six months post-surgery (T3), 12 months post-surgery (T4)	Chinese version of the Hospital Anxiety and Depression Scale (HADS) was used in this study to assess the anxiety and depression of elderly cancer patients, which was developed by Zigmond AS et al. The scale consists of 14 items, including anxiety and depression subscales. Each item is rated on a 4 point scale, and the scores of the anxiety and depression scales range from 0 to 21 points. The Cronbach's α coefficient of the HADS for this study was 0.85.
depression	immediately after surgery (T1), three month post-surgery (T2), six months post-surgery (T3), 12 months post-surgery (T4)	Chinese version of the Hospital Anxiety and Depression Scale (HADS) was used in this study to assess the anxiety and depression of elderly cancer patients, which was developed by Zigmond AS et al. The scale consists of 14 items, including anxiety and depression subscales. Each item is rated on a 4 point scale, and the scores of the anxiety and depression scales range from 0 to 21 points. The Cronbach's α coefficient of the HADS for this study was 0.85.

Trial Locations

Locations (1)

Yinning Guo; 🇨🇳 Nanjing, Jiangsu, China