Renal Resistive Index as an Indicator of Lupus Nephritis Severity and Systemic Lupus Activity

Not Applicable

Completed

• Conditions: Systemic Lupus Erthematosus; Lupus Glomerulonephritis; Lupus Flare

• Registration Number: NCT06757725
• Lead Sponsor: Kasr El Aini Hospital

Brief Summary

The study explores the role of the colour Doppler scanning of the renal arteries and its relation to the degree of disease affection in lupus nephritis

Detailed Description

we have recruited patients into 3 groups The first group is patients with lupus nephritis The second groups is patients with systemic lupus erythromatosus without nephritis The third groups is normal healthy controls we explored the association of colour Doppler and the renal resistive index with the degree of the renal affection in lupus nephritis

Study Timeline

• Study Start: 2022-09-03
• Primary Completion: 2023-10-13
• Study Completion: 2023-10-15
• Status Verified: 2024-12
• Study First Submitted: 2024-12-27
• Study First Submitted QC: 2024-12-27
• Last Update Submitted: 2024-12-27
• Study First Posted: 2025-01-03
• Last Update Posted: 2025-01-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• 1. Systemic lupus erythematosus. 2. Lupus nephritis. 3. Adults >18 years old.

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Exclusion Criteria

• 1. End Stage Renal Disease. 2. Diabetes Mellitus. 3. Heart failure. 4. Hepatic diseases. 5. Obstructive nephropathy. 6. Renal artery stenosis or occlusion.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Resistive index	At the time of recruitment	The resistive index of the renal arteries as measured by the colour Doppler

Trial Locations

Locations (1)

Cairo University Hospitals; 🇪🇬 Cairo, Egypt