To compare the effect of vapour and injection form of Tranexamic acid in the treatment of coughing of blood
Phase 2
- Conditions
- Health Condition 1: J988- Other specified respiratory disordersHealth Condition 2: J988- Other specified respiratory disorders
- Registration Number
- CTRI/2024/03/063698
- Lead Sponsor
- Indian council of medical research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients who are above 18 years of age will be recruited in the study
Exclusion Criteria
1.Patients already received tranexamic acid before presenting to the hospital.
2.Intubated patients on mechanical ventilation.
3.Patients with massive life-threatening hemoptysis who need to be immediately shifted for interventional procedures.
4.Patients not giving consent for participation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Cessation of bleeding in patients presenting to ED with active hemoptysis at 6 hours after TA administration in both arms <br/ ><br>2.Reduction in volume of hemoptysis at 6 h, 12 h, 24 h, 36 h and 48 h after TA administration in both armsTimepoint: 6 hours(h), 12 h, 24 h, 36 h and 48 h after TA administration in both arms
- Secondary Outcome Measures
Name Time Method 1.Need for interventional procedures on ED basis and adverse effects of TA administration during ED stay for 72 hours <br/ ><br>2.D-dimer and fibrinogen levels on arrival and at 24 and 48 hours of ED stayTimepoint: 24, 48 and 72 hours