Ivabradine versus metoprolol for heart rate reduction before coronary computed tomography angiography: a randomised trial

Completed

• Conditions: Coronary artery disease; Circulatory System; Chronic ischaemic heart disease

• Registration Number: ISRCTN74875961
• Lead Sponsor: Medical University of Vienna (Austria)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-10-01
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1. Sinus rhythm
2. Heart rate greater than or equal to 60 bpm
3. Systolic blood pressure greater than or equal to 100 mmHg
4. Aged greater than or equal to 19 years irrespective of gender

Exclusion Criteria

1. Known allergy to iodinated contrast media
2. Impaired renal function (creatinine serum level greater than 1.5 mg/dl)
3. Thyroid disorder
4. Unstable clinical condition
5. Frequent premature heartbeats
6. Sick-sinus-syndrome
7. Sinoatrial block
8. Second or third degree AV-block
9. Previous pacemaker implantation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Heart rate reduction 60 - 180 minutes after medication

Secondary Outcome Measures

Name	Time	Method
Systolic blood pressure before versus after medication