Transcranial Magnetic Stimulation as a Treatment for Primary Progressive Aphasia

Phase 1

Recruiting

• Conditions: Aphasia, Primary Progressive; C10.574

• Registration Number: RBR-7rvw6cd
• Lead Sponsor: Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-11-22
• Last Update Posted: 19 December 2023
• Study Completion: 2024-07-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Diagnosis of Aphasia,Primary Progressive - APP(logopenic, grammatical or semantic subtypes) based on clinical evaluation and speech-language pathology evaluation; be able to read, understand and sign the consent form to participate in the research;patients of both genders

Exclusion Criteria

Contraindication to Transcranial Magnetic Stimulation: history of epilepsy, traumatic brain injury, metal implant in the head; patients under judicial guardianship

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
As a primary outcome of the study, it is expected to find a better performance of the participants in relation to language through the Montréal-Toulouse battery (MTL Brasil) and through the increase of the Addenbrooke (ACE-R) scores

Secondary Outcome Measures

Name	Time	Method
Regarding the secondary outcomes, we expect a reduction in the scores of the Geriatric Depression Scale - short version (GDS-15), reduction in the scores of the Assessment Scale of Psychosocial Impact of the Diagnosis of Dementia (AIPDD), of the Functional Activities Questionnaire (PFEFFER) and the Neuropsychiatric Inventory (NPI)