Is the sweet probiotic drink Yakult beneficial or harmful to teeth?

Not Applicable

Completed

• Conditions: Dental caries; Probiotics; Lactobacillus casei Shirota; Caries risk assessment; Yakult; Acidogenicity; Stephan curve; Dental caries susceptibility; Dental caries activity tests

• Registration Number: TCTR20150915002
• Lead Sponsor: Faculty of Dentistry Undergraduate Research Opportunities Programme

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2007-09-24
• Study Start: 2015-09-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

Healthy (no systemic diseases)

Exclusion Criteria

Smoker
Alcoholic
Pregnant
Taken prescription medication/antibiotics within 4 weeks prior to study start
Consumed probiotics/probiotic-containing beverages within 2 weeks prior to study start
Prior restorations on maxillary canines and premolars

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Area under the Stephan curve Before intervention (day 1); after 14 days intervention Area under Stephan curve (pH/time) bounded by curve and pH 5.5, after 10% sucrose challenge.,pH recovery time Before intervention (day 1); after 14 days intervention Duration between the two times the Stephan curve touched the horizontal line denoting pH 5.5,Lowest pH Before intervention (day 1); after 14 days intervention Minimum pH observed from the Stephan curve

Secondary Outcome Measures

Name	Time	Method
Salivary bacterial counts (mutans streptococci, Lactobacillus) Before intervention (day 1); after 14 days intervention Counts performed using Dentocult SM Strip mutans and LB test kits,Cariogram risk assessment Before intervention (day 1) Survey; mutans streptococci and Lactobacillus counts; salivary buffer capacity