Investigating the potential benefits of Yakult for the dental health of childre

Not Applicable

Completed

• Conditions: Dental caries; Probiotics; Lactobacillus casei Shirota; Yakult; Dental caries risk assessment; Acidogenicity; Stephan curve

• Registration Number: TCTR20150922002
• Lead Sponsor: Kaohsiung Chang Gung Memorial Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2010-08-21
• Study Start: 2015-09-22
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

Cooperative behaviour

Exclusion Criteria

Systemic disease
Habitual Yakult consumption
Restorations on maxillary canines or premolars

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Area under the Stephan curve (AUC) Before intervention (day 1); after 7 days intervention AUC (pH/time) bounded by curve and pH 5.5, after 10% sucrose challenge.,pH recovery time Before intervention (day 1); after 7 days intervention Duration between the two times the Stephan curve touched the horizontal line denoting pH 5.5,Lowest pH Before intervention (day 1); after 7 days intervention Minimum pH observed from the Stephan curve

Secondary Outcome Measures

Name	Time	Method
Salivary counts of mutans streptococci bacteria Before intervention (day 1); after 7 days intervention Counts performed using Dentocult SM Strip mutans test kit,Salivary counts of Lactobacillus bacteria Before intervention (day 1); after 7 days intervention Counts performed using Dentocult LB test kit,Cariogram risk assessment Before intervention (day 1); after 7 days intervention Survey; mutans streptococci and Lactobacillus counts; salivary buffer capacity