Effects of fermented milk on prevention of antibiotic-associated diarrhoea and Clostridium difficile infection in patients undergoing planned bone surgery

Not Applicable

Completed

• Conditions: Digestive System; Infections; 1. Antibiotic-associated diarrhoea 2. Clostridium difficile infection

• Registration Number: ISRCTN12619517
• Lead Sponsor: St George's University of London

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2014-08-01
• Study Start: 2015-01-18
• Last Update Posted: 3 March 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1100

Inclusion Criteria

1. Undergoing elective joint replacement surgery at the Elective Orthopaedic Centre (UK)
2. Must be able to adhere to the protocol requirements
3. Must be capable of giving informed consent
4. At least 18 years old

Exclusion Criteria

1. Diarrhoea on pre-admission or within the preceding week
2. Lactose intolerance or intolerance to dairy products
3. Regular probiotic consumption in the previous 8 weeks
4. Antibiotic use in the previous 4 weeks
5. Patients unable to give written informed consent
6. Immunosuppression
7. Active inflammatory bowel disease or bowel surgery less than 6 months ago, cancer, leukaemia or pancreatitis

Study & Design

• Study Type: Interventional
• Study Design: Not specified