EUCTR2007-004616-31-NL进行中(未招募)不适用
Prevention of neutrophil induced extracellular matrix damage following skin exposure to solar simulating radiation (SSR) - Prevphotoag
niversitair Medisch Cemtrum Utrecht0 个研究点开始时间: 2007年10月18日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- adult, male or female, aged 18-55 years.
- •- healthy white skinned volunteers (skin photo type I-III).
- •- volunteers must be willing and able to give written informed consent.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years)
- •F.1.3.1 Number of subjects for this age range
排除标准
- •- sunlight allergy.
- •- tendency to hypertrophic scar or keloid formation.
- •- history of alcohol or drug abuse.
- •- treatment with phototherapy or systemic (immunosuppressive) therapy such as oral steroids and cyclosporin A during the study, or within 24 weeks prior to the study.
- •- Chronic treatment with phototherapy (duration > 1 year) and regular exposure of buttock-skin to sunlight or artificial UV-sources
- •- treatment with oral and local antibiotics.
- •- treatment with topical steroids or tar in the tested locations during the last 2 weeks.
- •- clinically relevant cardiovascular, gastrointestinal, liver or renal disease and/or unstable metabolic or endocrine disorders.
- •- acute or chronic local bacterial, viral or fungal diseases.
- •- women of childbearing potential not using reliable contraception
- •- pregnancy or breast feeding.
- •- psychiatric disease or history of noncompliance which, in the investigator’s assessment would interfere with appropriate protocol treatment and monitoring.
- •- patients visiting the hospital.
- •- persons who are situated in a dependant position in relation to the investigators.
研究者
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