NL-OMON31680已完成不适用
Prevention of neutrophil induced extracellular matrix damage following skin exposure to solar simulating radiation (SSR) - Prevphotoag
niversitair Medisch Centrum Utrecht0 个研究点目标入组 20 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- adult, men or women, aged 18-55 years.
- •- healthy white skinned volunteers (skin photo type I-IV).
- •- volunteers must be willing and able to give written informed consent.
排除标准
- •- contact allergy for any one of the applied topical products
- •- sunlight allergy.
- •- tendency to hypertrophic scar or keloid formation.
- •- history of alcohol or drug abuse.
- •- treatment with phototherapy or systemic (immunosuppressive) therapy such as oral steroids and cyclosporin A during the study, or within 24 weeks prior to the study.
- •- chronic treatment with phototherapy (duration > 1 year) and regular exposure of buttock skin to sunlight or artificial UV-sources.
- •- treatment with oral and local antibiotics.
- •- treatment with topical steroids or tar in the tested locations during the last 2 weeks.
- •- clinically relevant cardiovascular, gastrointestinal, liver or renal disease and/or unstable metabolic or endocrine disorders.
- •- acute or chronic local bacterial, viral or fungal diseases.
- •- women of childbearing potential not using reliable contraception
- •- pregnancy or breast feeding.
- •- psychiatric disease or history of noncompliance which, in the investigator*s assessment would interfere with appropriate protocol treatment and monitoring.
- •- patients visiting the hospital.
- •- persons who are situated in a dependant position in relation to the investigators.
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