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Assessing the effects of brain stimulation on sleep in people with insomnia

Not Applicable
Suspended
Conditions
Insomnia
Mental and Behavioural Disorders
Nonorganic insomnia
Registration Number
ISRCTN61956079
Lead Sponsor
niversity of Oxford
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Suspended
Sex
All
Target Recruitment
40
Inclusion Criteria

Current inclusion criteria as of 11/03/2020:
1. Participant is willing and able to give informed consent for participation in the study
2. Male or female, aged 18-65 years
3. Screening positive for persistent insomnia (chronicity >3 months) as indicated on the Sleep Condition Indicator
4. Sleep onset difficulties with or without sleep maintenance problems
5. Increased pre-sleep arousal (pre-sleep arousal scale)
6. Score = 2 on the Sleep Condition Indicator questions 5 or 6 (daytime impairment)
7. Typical sleep period takes place within the hours of 10 pm – 9 am
8. Can read and understand English
9. Normal or corrected to normal vision (visual, computer-based, tasks comprise part of the experiment)

_____
Previous inclusion criteria:
1. Participant is willing and able to give informed consent for participation in the study
2. Male or female, aged 25-65 years
3. Screening positive for persistent insomnia (chronicity >3 months) as indicated on the Sleep Condition Indicator
4. Sleep onset difficulties with or without sleep maintenance problems
5. Increased pre-sleep arousal (pre-sleep arousal scale)
6. Score = 2 on the Sleep Condition Indicator questions 5 or 6 (daytime impairment)
7. Typical sleep period takes place within the hours of 10 pm – 9 am
8. Can read and understand English
9. Normal or corrected to normal vision (visual, computer-based, tasks comprise part of the experiment)
10. Right handed

Exclusion Criteria

Current exclusion criteria as of 11/03/2020:
1. Unstable physical or mental health problems that may explain sleep disturbance
2. Probable additional sleep disorders (e.g. sleep-disordered breathing or periodic leg movements during sleep assessed via questionnaire and interview)
3. Habitual night shift, evening, or rotating shift-workers
4. Undergoing a psychological treatment programme for insomnia with a health professional
5. Medication use (central nervous system agents including hypnotics)
6. Previous participation in tDCS study
7. Substance abuse
8. Pregnancy
9. Psychosis or epilepsies
10. A score within the clinical range for depression (>14) or anxiety (>14) on Hospital Anxiety and Depression Questionnaire (HADS)
11. Learning disability
12. Skin allergies or very sensitive skin
13. Diagnosis of a neurological condition (e.g. epilepsy, stroke, multiple sclerosis)
14. Contraindications to tDCS (including, but not limited to metal in the head or medical devices implanted in the brain, epilepsy)

_____
Previous exclusion criteria:
1. Unstable physical or mental health problems that may explain sleep disturbance
2. Probable additional sleep disorders (e.g. sleep-disordered breathing or periodic leg movements during sleep assessed via questionnaire and interview)
3. Habitual night shift, evening, or rotating shift-workers
4. Undergoing a psychological treatment programme for insomnia with a health professional
5. Medication use (central nervous system agents including hypnotics)
6. Previous participation in tDCS study
7. Substance abuse
8. Pregnancy
9. Psychosis or epilepsies
10. A score within the clinical range for depression (>7) or anxiety (>10) on Hospital Anxiety and Depression Questionnaire (HADS)
11. Learning disability
12. Skin allergies or very sensitive skin
13. Diagnosis of a neurological condition (e.g. epilepsy, stroke, multiple sclerosis)
14. Contraindications to tDCS (including, but not limited to metal in the head or medical devices implanted in the brain, epilepsy)

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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