Effect of Ventilation strategy in patients undergoing Open Abdominal Surgeries in Trendelenburg position.
- Conditions
- Health Condition 1: C539- Malignant neoplasm of cervix uteri, unspecifiedHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2022/11/047449
- Lead Sponsor
- IMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Patients with 18-65years of age
2.either gender
3. patients undergoing elective open abdominal surgeries in trendelenburg position
4.surgery duration of greater than 2hours
5.American Society of Anesthesiologists (ASA) physical status I,II,III .
1.Refusal to participate in the study
2.Preexisting significant cardiac or pulmonary co morbidities (heart failure, intractable shock, Chronic obstructive pulmonary disease, Asthma, pulmonary infection, bronchiectasis, pulmonary metastases)
3.Preexisting abnormalities on chest X-ray or spirometry.
4.History of neuromuscular disease
5.Liver cirrhosis (Child B or C), or chronic renal failure with hemodialysis, and the
6.Need to continue prolonged mechanical ventilation after surgery.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method intra- and postoperative changes in P/F.Timepoint: intra- and postoperative changes in P/F, PaO2 before induction, 1hour after intubation and postoperative day 1
- Secondary Outcome Measures
Name Time Method differences between the two groups regarding PaO2, A-aO2; intraoperative Cdyn and Stat, and the incidence of atelectasis detected on chest x-ray on the first postoperative day.Timepoint: differences between the two groups regarding PaO2, A-aO2; intraoperative Cdyn and Stat after intubation,30min after intubation,60min before extubation and at extubation, and the incidence of atelectasis detected on chest x-ray on the first postoperative day.